What are GLP-1 Agonists?
GLP-1 agonists are medications designed to manage blood sugar levels in people with Type 2 diabetes and assist with weight loss in cases of obesity. These injectable medications mimic the effects of the GLP-1 hormone, which helps regulate blood sugar, slow digestion, and increase feelings of fullness.
Common GLP-1 Medications:
Dulaglutide (Trulicity®)
Exenatide (Byetta®, Bydureon®)
Liraglutide (Victoza®)
Semaglutide (Ozempic®, Rybelsus®)
Tirzepatide (Mounjaro®)
How They Work:
GLP-1 agonists trigger insulin release, reduce glucagon secretion, and slow stomach emptying. They also enhance satiety, reducing hunger and calorie intake—leading to better blood sugar control and potential weight loss.
Who Can Use GLP-1 Agonists?
They are FDA-approved for Type 2 diabetes and obesity. Providers may recommend them if other treatments like metformin are ineffective. These medications are not yet approved for Type 1 diabetes but are sometimes prescribed off-label.
Benefits:
Lowers blood sugar
Promotes weight loss
May reduce blood pressure and improve lipid profiles
Could lower risks of heart and kidney diseases
Potential Side Effects:
Common issues include nausea, vomiting, and diarrhea, especially at the start. Rare but serious risks include pancreatitis and thyroid cancer. Pregnant individuals should avoid GLP-1 agonists.
Important Considerations:
GLP-1 agonists are not standalone treatments. They work best when combined with lifestyle changes, diet, and exercise. Regular follow-ups with your healthcare provider are essential to ensure safety and effectiveness.
When to Contact Your Provider:
Reach out if side effects occur, if the medication doesn’t seem effective, or if you’re considering pregnancy.
GLP-1 agonists offer an innovative way to manage Type 2 diabetes and obesity. Speak with your healthcare provider to determine if they fit your treatment plan. If you need assistance or information about GLP-1 products please contact us.
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